How much of the coronary calcium seen on CT is real, and how much is image artifact? In this episode of Behind the Science, Adith Arun sits down with Dr. Doosup Shin to discuss their JACC study, "Photon-Counting Detector CT Reduces Calcium Overestimation Compared with Energy-Integrating Detector CT: Micro-CT…
How much cardiovascular risk is hidden in the scans we already perform every day? In this episode of Behind the Science, we explore groundbreaking research on imaging-derived sarcopenic obesity and its relationship to heart failure, cardiovascular death, and overall mortality. The discussion highlights how routine…
In this episode of Behind the Science, Dr. Yogesh Reddy joins to explore how sotatercept improves outcomes in pulmonary arterial hypertension (PAH) and why its effects go beyond traditional vasodilation. Using detailed invasive hemodynamic testing, exercise protocols, and skeletal muscle assessment, the study…
In this episode of Behind the Science, we sit down with Dr Yao to discuss the recent JACC publication, "The Prognostic Value of Serum Interleukin-6 Concentrations for 9 Cardiovascular and Mortality Outcomes: The Cross Cohort Collaboration (CCC)." The discussion explores the growing role of interleukin-6 (IL-6) as a…
In this episode of Behind the Science, Adith Arun is joined by Drs. Rahul Mahajan and Shaan Khurshid to discuss their recent JACC study on using artificial intelligence–enabled electrocardiograms (ECGs) to predict long-term stroke risk. Drawing on data from over 200,000 patients, the team demonstrates how a single…
In this episode of Behind the Science, host Adith Arun sits down with Dr. Evangelos Oikonomou to discuss groundbreaking research published in JACC: "Early Prediction of Heart Failure from Routine Cardiac CT Using Radiomic Phenotyping of Epicardial Fat." Dr. Oikonomou walks us through how AI-powered radiomic analysis…
In this episode of Behind the Science, we explore how coronary artery calcium scoring improves cardiovascular risk assessment in patients with elevated lipoprotein(a). This multicohort study highlights how Lp(a) and CAC serve as independent predictors of ASCVD and how combining both tools enhances risk stratification…
Listen in to JACC's perspective on our newest research, published on June 19 and featuring co-authors Adith Arun, BS, Clyde W. Yancy, MD, MSc. We present readers with another update in our Data Report Series, evaluating trends in excess cardiovascular mortality among Black Americans compared with White Americans from…
Dr. Aaysha Cader, Social Media editor for JACC Interventions and Dr. Chao Gao discuss the pre-specified subgroup analysis of the REC-CAGEFREE I trial: Drug-Coated Balloon Angioplasty vs Drug-Eluting Stents in Noncomplex Coronary Bifurcation Lesions.
Dr. Aaysha Cader, Social Media editor for JACC Interventions and Dr. Antoinette Neylon discuss the randomised KISS trial: Side Branch Additional Treatment for Coronary Bifurcation Lesion Revascularization.
Join us for the latest Behind the Science discussion, featuring an article published in JACC's May 12 focus issue on hypertension. Adith Arun, MD, joins author William B. White, MD, as they discuss a phase 2 randomized trial of the NPR1 agonist XXB750 in patients with resistant hypertension. The interview highlights…
In this interview in JACC's May 12 issue focusing on hypertension, JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, MACC speaks with first author Samantha S. O'Connell, MS, MD, as they discuss a comprehensive global analysis of hypertension trends from 2000 to 2020, drawing on data from nearly 300 population-based…
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