Behind the Science: Can IL-6 Improve Cardiovascular Risk Assessment? Findings From the CCC Study | JACC Author Interviews

In this episode of Behind the Science, we sit down with Dr Yao to discuss the recent JACC publication, "The Prognostic Value of Serum Interleukin-6 Concentrations for 9 Cardiovascular and Mortality Outcomes: The Cross Cohort Collaboration (CCC)." The discussion explores the growing role of interleukin-6 (IL-6) as a key inflammatory biomarker in cardiovascular disease and its potential value beyond traditional markers such as high-sensitivity C-reactive protein (hsCRP). Drawing on data from more than 320,000 participants across multiple community-based cohorts, the study examined associations between IL-6 and nine major cardiovascular and mortality outcomes, including myocardial infarction, stroke, atrial fibrillation, heart failure, cardiovascular mortality, and all-cause mortality. #JACC #Cardiology #IL6 #Inflammation #CardiovascularDisease #HeartFailure #Prevention #Biomarkers #ClinicalResearch #BehindTheScience