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New HEDIS measures are changing the expectations around asthma follow-up, creating an important opportunity for primary care providers to look beyond the exacerbation itself. This episode explores the 2026 HEDIS Follow-Up After Acute and Urgent Care Visits for Asthma (AAF-E) measure and what clinicians should consider…
More than 1 in 4 children with food allergy live in food-insecure families, highlighting a challenge that extends well beyond allergen avoidance. This episode explores how food insecurity, socioeconomic status, access to care, insurance coverage, geographic barriers, medication affordability, and access to…
About 30% to 40% of the world’s population is affected by some form of allergic disease, making allergy a routine consideration in primary care. But as interest in the microbiome grows, clinicians and patients face an important question: what does the evidence actually tell us about its role in allergic disease? This…
Many diagnoses involve laboratory diagnostics, yet patients with autoimmune and allergic disease still face delayed or incomplete testing. In this live recording of ImmunoCAST from Lab Week 2026, featuring allergist Dr. Zachary Rubin and autoimmune specialist Dr. Crista Prates, we examine how laboratories can close…
A 7% sensitization rate by 3 months of age highlights how early allergic disease can begin, making early recognition critical for long-term patient outcomes. In this episode, internationally recognized allergy researcher and pediatric allergist Dr. Anna Asarnoj shares insights from the landmark BAMSE birth cohort and…
Few scientists have shaped modern allergy medicine as profoundly as Dr. Thomas Platts-Mills. From pioneering research on dust mite allergens and environmental drivers of asthma to helping uncover the IgE-mediated mechanism behind alpha-gal syndrome, his discoveries have transformed how clinicians diagnose and manage…
Dr. Ruchi Gupta, board-certified pediatrician and founding director of the Center for Food Allergy and Asthma Research (CFAAR), and PA Gary Falcetano joined forces on a Food Allergy Research and Education (FARE) webinar to discuss nuances and insights for managing food allergies across a patient’s life. In this…
Food allergy diagnosis is still too often driven by tests instead of history, leading to unnecessary restriction and missed opportunities for targeted care. In this episode, we invite Dr. Anna Nowak-Wegrzyn, a leading researcher in food allergy and Director of Pediatric Allergy and Immunology Division at NYU Grossman…
Asthma affects over 26 million people in the U.S., yet outcomes can vary dramatically based on factors beyond disease severity. This episode explores the critical gap between diagnosis and optimal asthma control, focusing on how socioeconomic status, access to care, and environmental exposures shape patient outcomes…
With 29 million golfers in the U.S. and an estimated 7.25 million affected by spring allergies, seasonal respiratory symptoms can meaningfully affect performance and daily function. This episode explores how tree and grass pollen exposure, overlapping sensitizations, and indoor allergens can combine to drive rhinitis…
A large 2024 study found that a comprehensive respiratory allergen profile captured more than 98% of seasonal sensitizations, highlighting a major challenge in respiratory allergy care: testing with single allergens can miss the full picture. In this episode, we explore the most optimized regional respiratory profiles…
Wheat allergy, celiac disease, and non-specific gluten intolerance all share overlapping gastrointestinal symptoms that can confound primary care diagnosis. This episode addresses the core diagnostic challenge of distinguishing IgE-mediated wheat allergy (including ω-5 gliadin–associated wheat-dependent…
Celebrate our 50th episode by diving in to hear some of our favorite insights from the many allergy experts we’ve welcomed to ImmunoCAST. In this episode, we’ve curated clinical clips from guests like Dr. Zachary Rubin, Dr. David Golden, Dr. Ruchi Gupta, and more. From the mental health impacts of food allergy to the…
Nearly 11% of U.S. adults meet criteria for a convincing food allergy, yet most clinicians underestimate both the prevalence and unique challenges of adult-onset disease. This episode addresses the frequent misdiagnosis and clinical uncertainty surrounding new symptoms in adults by highlighting epidemiology, risk…
For primary care providers, seeing a patient presenting with atopic dermatitis (eczema) is common, yet misconceptions persist regarding its underlying cause and optimal management. This episode tackles the critical clinical dilemma: when and how should specific IgE testing for food and environmental allergens shape…
In this episode, we sit down with ImmunoCAST host Gary Falcetano, PA, to discuss the insights he wishes he had when he first began treating and managing allergy patients, along with the knowledge he has gathered from speaking with thousands of clinicians across the country. Gary addresses common misconceptions…
Over 99% of homes contain at least one allergen, with 75% harboring three to six, yet winter allergies often masquerade as stubborn “colds” or recurrent respiratory infections. This episode confronts the core diagnostic challenge of differentiating allergy-driven symptoms from viral, bacterial, or non-allergic…
In this episode, we tackle the challenge of separating allergy fact from fiction in an age of rampant online misinformation. Dr. Zachary Rubin, a double board-certified pediatrician and allergist, shares insights on common allergy myths circulating on social media. We explore misconceptions about food allergies vs…
Did you know that a dog allergy could be linked to unexplained infertility? This episode delves into fascinating allergy case studies and how component-resolved diagnostics can help uncover hidden connections. From wheat-dependent exercise-induced anaphylaxis in children to severe sesame reactions despite negative…
Imagine a child diagnosed with a life-threatening food allergy – how does this impact their mental health and family dynamics? In this episode, we explore the often-overlooked psychological aspects of food allergies. Licensed therapist Tamara Hubbard, MA, LCPC, shares insights on helping patients and families navigate…
Did you know that peanut-triggered anaphylaxis jumps by 85% during Halloween? This startling statistic underscores the critical need for healthcare providers to address food allergy management proactively. This episode tackles the complex interplay between food allergies and Halloween festivities, offering insights…
Did you know that up to 70% of adults with seasonal allergies may experience symptoms of pollen food allergy syndrome (PFAS)? This often-overlooked condition can mimic true nut allergies, leading to unnecessary dietary restrictions. In this episode, we tackle the challenge of differentiating PFAS from primary nut…
A tick bite in Maine leads to an unexpected diagnosis, challenging our understanding of alpha-Gal syndrome's geographic boundaries. This episode unravels the expanding reach of this unique allergic condition, now found from coast to coast and linked to multiple tick species. We explore recent case studies that…
Did you know that IgE, the antibody responsible for allergic reactions, is 30,000 times less abundant than other immunoglobulins in the body? This staggering fact underscores the importance of highly sensitive allergy diagnostics. In this episode, we pull back the curtain on what happens to allergy diagnostic blood…
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