Meet the Doc Who Put Hydroxychloroquine (and More) on Trial in COVID-19

Instead of trying therapies and hoping for the best, the RECOVERY trial investigators designed randomized trials to test which therapeutics were truly effective for COVID-19. Dr Harrington interviews lead investigator Martin Landray, MB ChB, PhD.

To read a transcript or to comment:

https://www.medscape.com/author/bob-harrington

The Bob Harrington Show is intended for healthcare professionals.

RECOVERY Trial Website and Some Publications

Randomized Evaluation of COVID-19 Therapy

https://www.recoverytrial.net/

Dexamethasone in Hospitalized Patients with Covid-19

https://www.nejm.org/doi/full/10.1056/nejmoa2021436

Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

https://doi.org/10.1016/S0140-6736(20)32013-4

Remdesivir for the Treatment of Covid-19 — Final Report https://www.nejm.org/doi/full/10.1056/nejmoa2007764

Dexamethasone in Hospitalized Patients with Covid-19 https://www.nejm.org/doi/full/10.1056/nejmoa2021436

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19

https://www.nejm.org/doi/full/10.1056/NEJMoa2022926

Clinical Trials and Informed Consent

The good Clinical Trials Collaborative

https://www.goodtrials.org/

Why do we need some large, simple randomized trials?

https://doi.org/10.1002/sim.4780030421

Assessment of Length and Readability of Informed Consent Documents for COVID-19 Vaccine Trials

http://jamanetwork.com/article.aspx?doi=10.1001/jamanetworkopen.2021.10843

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