Season 8 • Episode 121

The 229 Podcast: Breach Simulations and the CISO Burnout Epidemic with Anahi Santiago

Oct 16, 2025

33:36

Global Health Physician Burnout & Wellness Medical Devices Emerging Infections Pediatric Oncology Patient Safety & Quality

Episode Description

October 16, 2025: How do you build a cybersecurity program that lasts over a decade? Anahi Santiago, CISO at ChristianaCare, shares what separates healthcare organizations that prioritize security from those where CISOs burn out in 18 months. She reveals why bringing state agencies and the National Guard into tabletop exercises transformed her team's preparedness, how she aligned security with patient safety from day one, and why healthcare's open environments create unique challenges that other industries never face. From managing 70,000 medical devices to building operational resilience across multiple states, Anahi offers hard-won insights on creating a culture where cybersecurity thrives—not just survives. Key Points:

01:04 The Role and Longevity of a CISO
04:58 Unique Challenge of Healthcare Cyber
13:41 Tabletop Exercises and Preparedness
19:33 Creating a Culture of Security
27:36 Sports Analogies and Leadership in Healthcare

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