Health Podcast Library

How GPx is turning a smartwatch into an early warning system for heart failure

Aug 7, 2026
14:17

Episode Description

Heart failure patients are often living in a black box – not knowing how they're really doing until they end up in the ER. StartUp Health community member Sean Matsuoka, CEO & Co-founder of General Prognostics (GPx), explains how his team built an algorithm that reads wearable device data alongside a trusted blood biomarker to give doctors an early signal, days before a crisis.

In this Health Moonshot Update, Matsuoka talks with StartUp Health's Logan Plaster about the personal story behind GPx, why device-agnostic design matters, the operational challenge of running a distributed clinical trial, and how the company plans to get reimbursed through existing Medicare and Medicaid codes.

Every Health Transformer has a story like this one. If you're building in health innovation, join StartUp Health and we can help you tell yours.

Proudly Supported by

Patrons of Health Podcast Library

AAOS Career Podcast
OrthoInfo
Achieving Health
AAOS Now Podcast
Stronger After Stroke
Aging Like a Pro

Supporting Shows

Hopeful Hints
Faces of Digital Health
Healthcare for Humans
Coffee Break: Breaking the Cycle of Bullying in Healthcare, One Cup at a Time
Beyond The Paper Gown Podcast
Speak Up For Your Health
HIT Like a Girl Pod: Empowering Women in Health IT
This Just In Radio Show
Thriving with Addiction with Dr. Jonathan Avery
Cuts and Consults