Skip to main content
Health Podcast Library
Episode 155

Breaking Free From Depression

Episode Description

Depression is often mistaken for ordinary sadness, but clinically it is something profoundly different: a medical illness that can alter the way the brain processes emotion, motivation, and even hope itself.

In this episode of Road to Resilience, host Stephen Calabria speaks with James Murrough, MD, PhD, to discuss how groundbreaking neuroimaging research explains why depression may leave the brain "entrapped" in inefficient patterns of activity, 

The conversation explores the difference between sadness and clinical depression, why chronic stress can reshape the brain, how behavioral therapy and medication help people break free from depression's grip, and why the brain's extraordinary capacity for change offers genuine reason for hope.

Visit https://www.mountsinai.org/clinical-trials to see if you're eligible to enroll in a clinical trial with the Mount Sinai Health System.

Check out more episodes of Road to Resilience —as well as guest pictures, transcripts, and more— on the Mount Sinai website.

If this episode inspired you, please consider supporting the Mount Sinai Health System. As a registered 501(c)(3) nonprofit, we rely on philanthropy to advance compassionate patient care, groundbreaking research, and medical education. Your generosity helps make conversations like this possible—and fuels the work behind them. To learn more or make a gift, visit give.mountsinai.org.

Visit https://www.mountsinai.org/clinical-trials to see if you're eligible to enroll in a clinical trial with the Mount Sinai Health System. Check out more episodes of Road to Resilience—as well as guest pictures, transcripts, and more—on the Mount Sinai website.

Proudly Supported by

HeadlinerBetterHelpForvis MazarsAAOSCalendarPAmowPod

Patrons of Health Podcast Library

Achieving Health
AAOS Career Podcast
OrthoInfo
AAOS Now Podcast
Who the Health Cares? with Prof Michael Sparer
Stronger After Stroke
Aging Like a Pro

Supporting Shows

Thriving with Addiction with Dr. Jonathan Avery
Coffee Break: Breaking the Cycle of Bullying in Healthcare, One Cup at a Time
Coaching Healthcare Leaders
On the Pulse Podcast
Healthcare for Humans
Impulse | Meeting Healthcare Pioneers
HIT Like a Girl Pod: Empowering Women in Health IT
Hopeful Hints
HITea With Grace
Beyond The Paper Gown Podcast
This Just In Radio Show
Cuts and Consults
Nurse Rosa's INsights
Faces of Digital Health
Speak Up For Your Health

We use cookies to run this site. Analytics cookies help us understand how you use it and are off until you say yes. You can change your mind at any time from the privacy preferences icon at the bottom right.We use cookies to run this site and to understand how it's used. You can opt out at any time from the privacy preferences icon at the bottom right. Cookie policy