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Episode 598

Pioneering A More Humane Cancer Treatment: Dr. Hadiyah-Nicole Green, Founder & President, Ora Lee Smith Cancer Research Foundation

Sep 17, 2026
44:11

Episode Description

Limiting the side effects of cancer treatments has been an animating force in the field of oncology for many years, and there’s been progress to report on that front, but what if you could target cancer tumors without using radiation or chemotherapy and instead generate heat from inside the tumor to kill cells?

That’s the quest of our guest today, Dr. Hadiyah-Nicole Green, whose promising research using lasers and nanoparticles to eliminate tumors received Breakthrough Device Designation from the FDA earlier this year. “The laser beam that we're using is low power like a laser pointer, and without activation by the laser, the nanoparticles are harmless. Both are targeted just at the site of the tumor so because we don’t use systemic delivery, we avoid all of the systemic side effects,” she explains.

Dr. Green is also the founder and president of the Ora Lee Smith Cancer Research Foundation, named for an aunt who raised her and who died of cancer without pursuing curative treatment because of her fear of the side effects. Shortly after, her aunt’s husband also died of cancer, opting for treatments that took a heavy toll on his body. “At 22 years old, I saw the horrors of cancer and the horrors of cancer treatment and just felt in my heart that there has to be something better than this,” she tells host Michael Carrese.

On this fascinating episode of Raise the Line from Elsevier, we'll explore the science behind Dr. Green's approach, the challenges of raising the millions of dollars needed for human clinical trials, and rethinking the current funding landscape for cancer treatments.

Mentioned in this episode:
Ora Lee Smith Cancer Research Foundation

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