Feasibility and Safety of Strategic Multielectrode Positioning Guided by S3 Protocol for Hemodynamically Unstable Ventricular Tachycardia: The S3-STaMP Project | JACC: Clinical Electrophysiology

Francis E. Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses the S3-STaMP study, which evaluated a novel mapping strategy for patients with hemodynamically unstable ventricular tachycardia (VT). The investigators found that STaMP mapping, guided by the S3 functional mapping protocol, rapidly identified critical VT circuit pathways in nearly three-quarters of patients and did so without causing acute hemodynamic deterioration. These findings suggest that S3-guided STaMP mapping may offer a safe and practical approach to improve catheter ablation of otherwise difficult-to-map VT.