Primary Tricuspid Regurgitation and TEER: Insights from an International Cohort | JACC Baran

Hosts Mitsuaki Sawano, MD, and Nobuhiro Ikemura, MD, welcome Dr. Atsushi Sugiura to discuss transcatheter edge-to-edge repair (TEER) for primary tricuspid regurgitation (TR). Dr. Sugiura reviews findings from a retrospective, international, multicenter cohort study of 114 high-surgical-risk patients with primary TR who underwent TEER. In this cohort, TR was graded as moderate or less at discharge in 83% of patients, with an in-hospital mortality rate of 1.8%. At one year, most patients continued to have TR at moderate or less, along with observed changes in right heart dimensions and NYHA functional class. One-year mortality and heart failure rehospitalization rates were similar to those observed in a surgical repair cohort. These results describe procedural and clinical outcomes of TEER in a high-risk primary TR population across centers in Germany, Switzerland, and the United States.