JACC Editor's Page

Two years into his role as Editor-in-Chief, Dr. Harlan Krumholz looks back on the journey that's shaped JACC, staying true to its mission while evolving to better serve authors and readers around the world. He shares what's driven the journal's growth into a truly international platform and offers a glimpse of where…

Dr. Harlan Krumholz reflects on the profound impact of experiencing a patient's death for the first time, describing how medical training often leaves clinicians unprepared for the emotional and communicative challenges that follow. Over time, he developed a compassionate framework for speaking with grieving…

In this week's Editor's Page, Dr. Harlan Krumholz introduces Dr. Milton Packer's adipokine hypothesis, which proposes that dysfunctional visceral fat and the adipokines it secretes are central to the development of heart failure with preserved ejection fraction (HFpEF). This framework suggests that the benefits of…

In the Editor's Page for the JACC October 14, 2025 issue, JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, critiques the current physician certification system, arguing it is outdated, misaligned with real-world clinical practice, and contributes to physician burnout without clear evidence of improved patient…

In this week's Editor's Page, Dr Harlan Krumholz explains how the rise of AI writing tools marks a turning point in scientific communication, offering support for grammar, clarity, and structure—especially benefiting those less fluent in English or academic conventions.

Artificial intelligence is rapidly transforming cardiovascular medicine, offering breakthroughs in diagnosis, treatment personalization, and research acceleration. However, its responsible integration requires guiding principles: focusing on clinical problems over technology, rigorous evaluation, bias mitigation…

In June 2025, the White House introduced "Gold Standard Science" principles to enhance the rigor, transparency, and trustworthiness of federally funded research—values long embraced by top journals like JACC. These include reproducibility, openness to null results, interdisciplinary collaboration, and unbiased peer…

This week's Editor's Page outlines JACC's expectations for AI research manuscripts in cardiovascular care, emphasizing the need for clinical relevance, real-world feasibility, and responsible evaluation beyond retrospective model performance. We present a framework focusing on three core domains: addressing a genuine…

JACC's September 2 issue features a new editor's page from Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC. In it, he brings up a troubling stagnation and reversal in U.S. cardiovascular health progress since 2010, despite advances in medical treatments and increased healthcare spending. Click here to listen to this…

This update to the JACC Report Card highlights ongoing disparities in cardiovascular mortality between Black and White Americans. While some metrics, such as ischemic heart disease, show modest improvement, excess age-adjusted mortality rates and years of potential life lost remain alarmingly high for Black Americans…

Cardiovascular devices are at the heart of modern clinical practice, yet gaps in surveillance, reporting, and clinician awareness continue to pose serious risks to patient safety. This week's Editor's Page highlights the urgent need for improved transparency, stronger reporting systems, and clinician-led engagement…

Therapeutic breakthroughs in ATTR cardiomyopathy have ushered in a new era of treatment, with gene silencers, stabilizers, and next-generation therapies extending life and improving quality for patients once left with few options. Yet this progress has exposed a profound and growing divide—between innovation and…