BCC Treatment Goes Viral: Find out what happens when you unleash a genetically modified herpes virus on difficult BCCs

• Litfulo for when all hope for hair seems lost...when Olumiant strikes out, can Litfulo pinch hit and save the day?
• Hand eczema: Did we really need a 60,000-patient study to find out who's most likely to have horrible hands?
• The Hand Eczema Whisperer: Jacob Thyssen joins us all the way from the University of Copenhagen for some hand-to-hand combat: What causes it, what can you do about it right now, and what's on the horizon for hand eczema.
• But that's not all — the Derms on Drugs always bring the best stuff from the literature.

Derms on Drugs is produced by Scholars in Medicine.

Jacob P. Thyssen, MD, PhD, DmSci 

Dr. Thyssen has spent nearly 20 years as a clinical dermatologist at university hospitals in Copenhagen, where he currently serves as a professor emeritus. His research in inflammatory skin diseases and allergy has earned him numerous awards. Dr. Thyssen has co-authored more than 700 peer-reviewed articles, with his work appearing in prestigious journals such as The Lancet and NEJM. He holds PhD and medical doctor degrees and has been a research fellow at Harvard Medical School, Boston, UCSF in San Francisco, and a visiting professor at UZH in Zürich. 

Resources:

1.  Efficacy and tolerability of neoadjuvant therapy with Talimogene laherparepvec in cutaneous basal cell carcinoma: a phase II trial (NeoBCC trial)
https://pubmed.ncbi.nlm.nih.gov/39820126/
2.  Efficacy and Safety of Switching from Baricitinib to Ritlecitinib in Severe Alopecia Areata
https://pubmed.ncbi.nlm.nih.gov/39707907/
3.  Major improvement of very severe alopecia areata in patients treated with the combination of baricitinib and low doses of corticosteroids: an eight-case series
https://pubmed.ncbi.nlm.nih.gov/37467740/
4.  Prevalence of Chronic Hand Eczema in adults: A cross-sectional survey of over 60,000 respondents in the general population in Canada, France, Germany, Italy, Spain, and the United Kingdom
https://pubmed.ncbi.nlm.nih.gov/39797908/
5.  The Prevalence and Determinants of Hand and Face Dermatitis during COVID-19 Pandemic: A Population-Based Survey
https://pubmed.ncbi.nlm.nih.gov/33376481/
6.  Guidelines for diagnosis, prevention, and treatment of hand eczema
https://pubmed.ncbi.nlm.nih.gov/34971008/
7.  Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities
https://pubmed.ncbi.nlm.nih.gov/12603860/
8.  Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts
https://pubmed.ncbi.nlm.nih.gov/30936111/
9.  The Low Nickel Diet
https://www.thelownickeldiet.com/?gad_source=1&gclid=Cj0KCQiA-5a9BhCBARIsACwMkJ7Ah9ysdVxzpqlxk2KRJoUlUouvxmfcL6UzkNvmG7o8CIXjfNXlZnkaAlhYEALw_wcB
10.  Imiquimod Cream Preceded by Superficial Curettage vs Surgical Excision for Nodular Basal Cell Carcinoma: A Secondary Analysis of a Randomized Clinical Trial
https://pubmed.ncbi.nlm.nih.gov/39878970/
11.  Off-label use of tralokinumab in the treatment of bullous pemphigoid- a case series
https://pubmed.ncbi.nlm.nih.gov/39878153/
12.  Association between use of antihypertensives and treatment of actinic keratoses: A TriNetX population- based study
https://pubmed.ncbi.nlm.nih.gov/39894367/
13.  Perspectives on Artificial Intelligence-Generated Responses to Patient Messages
https://pubmed.ncbi.nlm.nih.gov/39412810/
14.  Sofdra prescribing information
https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/217347s000lbl.pdf
15.  A Pivotal Study on the Safety and Effectiveness of a Targeted Alkali Thermolysis Patch for Treatment of Primary Axillary Hyperhidrosis or Excessive Axillary Sweating
https://pubmed.ncbi.nlm.nih.gov/39480962/
16.  Impact of Needle Design and Suture Gauge on Tissue Tearing During Skin Suturing: A Comparative Analysis
https://pubmed.ncbi.nlm.nih.gov/39325023/