Fixing the Scales - How Re-Balancing Agents Work

In this episode of Ask the Experts, host Amy Board breaks down one of the most exciting developments in bleeding disorders treatment — rebalancing agents. Think of your body's clotting system like a seesaw: when everything's working right, it's balanced. But in bleeding disorders, the scale tips. Instead of adding what's missing (like clotting factors), rebalancing agents work by removing what's getting in the way — helping to restore that balance in a totally new way.

Amy is joined by Dr. Ben Samuelson Jones, Dr. Patrick Ellsworth, and Dr. Tami Singleton for a deep dive into how these therapies work, how they were inspired by what's already happening naturally in the body, and what makes them so promising. From TFPI antibodies to small interfering RNA treatments like Fitusiran, these cutting-edge approaches could transform care for many.

The experts also discuss the crucial role of patient participation in ongoing studies and why your voice matters in shaping the future of treatment. It's a hopeful, eye-opening conversation about how innovation is changing the game for bleeding disorders — and what comes next.

Presenting Sponsor:

Presented by Sanofi

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Show Notes:

Ask the Expert is produced by Believe Limited, and is found only on the BloodStream Media Podcast Network.

Presented by Sanofi

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