Behind the Science: What Muscle Health Reveals About Heart Failure Risk | JACC

How much cardiovascular risk is hidden in the scans we already perform every day? In this episode of Behind the Science, we explore groundbreaking research on imaging-derived sarcopenic obesity and its relationship to heart failure, cardiovascular death, and overall mortality. The discussion highlights how routine cardiac MRI can provide novel insights into muscle health, risk stratification, and the biological pathways linking obesity, aging, and cardiovascular disease. Join us as we examine how imaging, genomics, and transcriptomics come together to identify individuals at higher cardiovascular risk, uncover shared mechanisms between muscle loss and heart failure, and reveal new opportunities for precision cardiology.