Health Podcast Library
Episode 673

Cardiovascular-Kidney-Metabolic (CKM) Syndrome

Jun 30, 2026
29:31

Episode Description

Host: Darryl S. Chutka, M.D. 

Guest: Regis Fernandes, M.D. 

We’ve known for some time that patients who have hypertension and diabetes are at increased risk for developing subsequent cardiovascular disease and chronic kidney disease. It’s now being thought that these health problems are related and interconnected, representing Kidney-Cardiovascular Metabolic Syndrome. They form a pathophysiologic triad driven by shared mechanisms where disease in one system accelerates dysfunction in the others. So, what does this mean for primary care clinicians? Traditionally, we’ve managed hypertension, diabetes, cardiovascular disease, and chronic kidney disease as separate health conditions. It’s now felt that there may be a better approach. The topic for this podcast is “Kidney-Cardiovascular Metabolic Syndrome”, and my guest is Dr. Regis Fernandes, a preventive cardiologist at the Arizona campus of the Mayo Clinic. We’ll discuss the science, clinical implications, and recommended management strategies for this health condition. 

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